Article
A Plasmodium falciparum isolate with a chromosome 9 deletion expresses a trypsin-resistant cytoadherence molecule.
Molecular and biochemical parasitology - 1 Sept 1994
Chaiyaroj S C, Coppel R L, Magowan C, Brown G V
Abstract excerpt
Sequestration of Plasmodium falciparum infected erythrocytes in the cerebral circulation is strongly implicated in the pathogenesis of cerebral malaria. From previous studies it was postulated that genes essential for cytoadherence were located on the right arm of chromosome 9 as P. falciparum is...
Topics
- Animals
- CHO Cells
- Cell Adhesion
- Cell Adhesion Molecules
- Cell Line
- Chromosome Deletion
- Chromosome Mapping
- Cricetinae
- Endothelium, Vascular
- Erythrocytes
- Genes, Protozoan
- Humans
- Malaria
- Phenotype
- Plasmodium falciparum
- Protozoan Proteins
- Transfection
- Trypsin