Article
Competitive endothelial adhesion between Plasmodium falciparum isolates under physiological flow conditions.
Malaria journal - 21 Sept 2009
Phiri Happy, Montgomery Jacqui, Molyneux Malcolm, Craig Alister
Abstract excerpt
BACKGROUND: Sequestration of parasitized red blood cells in the microvasculature of major organs involves a sequence of events that is believed to contribute to the pathogenesis of severe falciparum malaria. Plasmodium falciparum infections are commonly composed of multiple subpopulations of parasites with varied adhesive properties. A key question is: do these subpopulations compete for adhesion to endothelium?...
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