Article
The promoter of the salmon insulin-like growth factor I gene is activated by hepatocyte nuclear factor 1.
The Journal of biological chemistry - 20 Jan 1995
Kulik V P, Kavsan V M, van Schaik F M, Nolten L A, Steenbergh P H, Sussenbach J S
Abstract excerpt
Hepatocyte nuclear factor 1 (HNF-1) was found to have a potent stimulatory action on the activity of the promoter of the salmon insulin-like growth factor I (IGF-I) gene in transient transfection experiments. This liver-enriched transcription factor was shown to bind to an element in the proximal region of the promoter with distinct nucleotide sequence homology to the HNF-1 consensus binding sequence. Mutating...
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