Article
The promoter of the salmon insulin-like growth factor I gene is activated by hepatocyte nuclear factor 1.
The Journal of biological chemistry - 20 Jan 1995
Kulik V P, Kavsan V M, van Schaik F M, Nolten L A, Steenbergh P H, Sussenbach J S
Abstract excerpt
Hepatocyte nuclear factor 1 (HNF-1) was found to have a potent stimulatory action on the activity of the promoter of the salmon insulin-like growth factor I (IGF-I) gene in transient transfection experiments. This liver-enriched transcription factor was shown to bind to an element in the proximal...
Topics
- Animals
- Base Sequence
- Cell Line
- DNA
- DNA-Binding Proteins
- Hepatocyte Nuclear Factor 1
- Hepatocyte Nuclear Factor 1-alpha
- Hepatocyte Nuclear Factor 1-beta
- Humans
- Insulin-Like Growth Factor I
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Promoter Regions, Genetic
- Protein Binding
- Salmon
- Transcription Factors
- Transcriptional Activation