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Article

Structure and Function of a Human Insulin-like Growth Factor-I Gene Promoter

1 Dec 1991

Abstract excerpt

We have identified and characterized a promoter regulatory region for the human insulin-like growth factor-I (IGF-I) gene. The 5'-ends of IGF-I mRNAs were first mapped to a series of sites within a 158-nucleotide portion of exon 1 that was found to be structurally similar to the recently delineated transcription start region of the chicken IGF-I gene. In both species multiple initiation sites are probably a...

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Identifiers

PMID: 1791841
DOI: 10.1210/mend-5-12-1964

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