Article
Liver-enriched HNF-3 alpha and ubiquitous factors interact with the human transferrin gene enhancer.
FEBS letters - 24 May 1993
Augé-Gouillou C, Petropoulos I, Zakin M M
Abstract excerpt
The human transferrin gene enhancer is organized in two domains. Domain A contains a single enhanson designated Ia. Domain B contains four enhansons named Ib, II, III and IV. We demonstrate here that the liver-enriched transcription factor HNF-3 alpha interacts with enhanson Ia and that enhansons...
Topics
- Base Sequence
- Cell Line
- DNA
- DNA-Binding Proteins
- Enhancer Elements, Genetic
- HeLa Cells
- Hepatocyte Nuclear Factor 3-alpha
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Protein Binding
- Sertoli Cells
- Transcription Factors
- Transferrin
