Article
Characterization of the mouse loricrin gene: linkage with profilaggrin and the flaky tail and soft coat mutant loci on chromosome 3.
Genomics - 15 Sept 1994
Rothnagel J A, Longley M A, Bundman D S, Naylor S L, Lalley P A, Jenkins N A, Gilbert D J, Copeland N G, Roop D R
Abstract excerpt
Loricrin is the major component of a specialized structure, termed the cornified cell envelope, that is formed beneath the plasma membrane of stratified squamous epithelial cells and is coexpressed with profilaggrin in terminally differentiating epidermal keratinocytes. Full-length cDNAs for both...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Mapping
- Cloning, Molecular
- Cricetinae
- DNA, Complementary
- Filaggrin Proteins
- Genetic Linkage
- Humans
- Hybrid Cells
- Intermediate Filament Proteins
- Introns
- Membrane Proteins
- Mice
