Loricrin and human skin diseases: molecular basis of loricrin keratodermas.

doi:10.14670/HH-13.819

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Article

Loricrin and human skin diseases: molecular basis of loricrin keratodermas.

Histology and histopathology - 1 Jul 1998

Ishida-Yamamoto A, Takahashi H, Iizuka H

Abstract excerpt

The cornified cell envelope (CE) is a tough structure formed beneath the plasma membrane of terminally differentiated keratinocytes. Recent progress in understanding the molecular organization of the CE has disclosed the complex, yet orderly structure that functions as a protective barrier agains...

Topics

Animals
Disease Progression
Gene Expression Regulation
Humans
Keratosis
Membrane Proteins
Mutation

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