The RTX haemolysins ApxI and ApxII are major virulence factors of the swine pathogen Actinobacillus pleuropneumoniae: evidence from mutational analysis.

doi:10.1111/j.1365-2958.1994.tb01282.x

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Article

The RTX haemolysins ApxI and ApxII are major virulence factors of the swine pathogen Actinobacillus pleuropneumoniae: evidence from mutational analysis.

Molecular microbiology - 1 Oct 1994

Tascón R I, Vázquez-Boland J A, Gutiérrez-Martín C B, Rodríguez-Barbosa I, Rodríguez-Ferri E F

Abstract excerpt

The involvement of the RTX haemolysins (ApxI and ApxII) of the swine pathogen Actinobacillus pleuropneumoniae in virulence was investigated using haemolysin-deficient mutants constructed by a mini-Tn10 mutagenesis procedure. Two types of haemolysin mutant with single insertions of the transposon...

Topics

Actinobacillus pleuropneumoniae
Amino Acid Sequence
Animals
Bacterial Proteins
Bacterial Toxins
Base Sequence
DNA Transposable Elements
Hemolysin Proteins
Hemolysis
Mice
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis

Mutation

Operon

Phenotype

Swine

Virulence

Source

Open in PubMed

Identifiers

PMID: 7830567
DOI: 10.1111/j.1365-2958.1994.tb01282.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7830567-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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