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Article

Characterization of apxlVA, a new RTX determinant of Actinobacillus pleuropneumoniae

1 Aug 1999

Abstract excerpt

A fourth type of RTX determinant was identified in Actinobacillus pleuropneumoniae and was designated apxIVA. When expressed in Escherichia coli, recombinant ApxIVA showed a weak haemolytic activity and co-haemolytic synergy with the sphingomyelinase (beta-toxin) of Staphylococcus aureus. These activities required the presence of an additional gene, ORF1, that is located immediately upstream of apxIVA. The apxIVA...

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PMID: 10463177
DOI: 10.1099/13500872-145-8-2105

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