Article
Molecular investigation of the role of ApxI and ApxII in the virulence of Actinobacillus pleuropneumoniae serotype 5.
Microbial pathogenesis - 1 Mar 1995
Reimer D, Frey J, Jansen R, Veit H P, Inzana T J
Abstract excerpt
The extracellular hemolytic toxins (ApxI and ApxII) of Actinobacillus pleuropneumoniae are thought to be important factors in this microorganism's virulence and the pathogenesis of swine pleuropneumonia. Using the polymerase chain reaction, the apxI locus of a non-hemolytic, avirulent mutant of A...
Topics
- Actinobacillus Infections
- Actinobacillus pleuropneumoniae
- Animals
- Bacterial Proteins
- Bacterial Toxins
- Base Sequence
- DNA Primers
- DNA, Bacterial
- Female
- Genes, Bacterial
- Hemolysin Proteins
- Mice
- Molecular Sequence Data
- Mutation
- Pleuropneumonia
- Polymerase Chain Reaction
- Recombination, Genetic
- Swine