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Article

Molecular investigation of the role of ApxI and ApxII in the virulence of Actinobacillus pleuropneumoniae serotype 5.

Microbial pathogenesis - 1 Mar 1995

Reimer D, Frey J, Jansen R, Veit H P, Inzana T J

Abstract excerpt

The extracellular hemolytic toxins (ApxI and ApxII) of Actinobacillus pleuropneumoniae are thought to be important factors in this microorganism's virulence and the pathogenesis of swine pleuropneumonia. Using the polymerase chain reaction, the apxI locus of a non-hemolytic, avirulent mutant of A. pleuropneumoniae serotype 5 (mIT4-H) generated by chemical mutagenesis (Inzana T. J., Todd J., Veit H. P. Microb...

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PMID: 7565014
DOI: 10.1016/s0882-4010(95)90049-7

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