Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Virulence in Actinobacillus pleuropneumoniae and RTX toxins.

Trends in microbiology - 1 Jul 1995

Frey J

Abstract excerpt

RTX toxins are pore-forming, cytolytic protein toxins that occur widely among pathogenic Gram-negative bacteria. RTX toxins appear to play a direct role in the virulence of Actinobacillus pleuropneumoniae, the etiological agent of porcine pleuropneumonia. This discovery has led to the development of new diagnostic and epidemiological tools, as well as vaccines, that are useful for a broad variety of serotypes.

Topics

Actinobacillus pleuropneumoniae
Animals
Bacterial Proteins
Genotype
Hemolysin Proteins
Phenotype
Virulence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7551637
DOI: 10.1016/s0966-842x(00)88939-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7551637-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Virulence in Actinobacillus pleuropneumoniae and RTX toxins.PMID 7551637Read ↗

Characterization of apxlVA, a new RTX determinant of Actinobacillus pleuropneumoniaeSemantic proximity Read ↗

Comparative genome analyses to understand the population biology and virulence of the pig pathogen Actinobacillus pleuropneumoniaeSemantic proximity Read ↗

New trends in innovative vaccine development against Actinobacillus pleuropneumoniae.Semantic proximity Read ↗

<i>In-silico</i> prediction and modeling of ApxA exotoxins of <i>Actinobacillus pleuropneumoniae:</i> ApxIA, -IIA, -IIIA and -IVASemantic proximity Read ↗

The role of RTX toxins in host specificity of animal pathogenic PasteurellaceaeSemantic proximity Read ↗

RTX Toxins of Animal Pathogens and Their Role as Antigens in Vaccines and DiagnosticsSemantic proximity Read ↗

RTX Toxins Ambush Immunity’s First Cellular RespondersSemantic proximity Read ↗

Development and use of a multiplex polymerase chain reaction assay based on Apx toxin genes for genotyping of Actinobacillus pleuropneumoniae isolates.Semantic proximity Read ↗

Knockout mutants of Actinobacillus pleuropneumoniae serotype 1 that are devoid of RTX toxins do not activate or kill porcine neutrophils.Semantic proximity Read ↗

RTX toxins in PasteurellaceaeSemantic proximity Read ↗

An Actinobacillus pleuropneumoniae PCR typing system based on the apx and omlA genes — evaluation of isolates from lungs and tonsils of pigsSemantic proximity Read ↗

Actinobacillus pleuropneumoniae iron transport and urease activity: effects on bacterial virulence and host immune response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.