Article
Altered pH and lysine signalling mutants of cadC, a gene encoding a membrane-bound transcriptional activator of the Escherichia coli cadBA operon.
Molecular microbiology - 1 Oct 1994
Dell C L, Neely M N, Olson E R
Abstract excerpt
The Escherichia coli CadC protein is required for activation of cadBA transcription under conditions of low external pH and exogenous lysine. cadBA encodes proteins involved in the decarboxylation of lysine to cadaverine, and cadaverine excretion. Sequence analysis suggested that CadC contains a...
Topics
- Bacterial Proteins
- Base Sequence
- Blotting, Western
- Carboxy-Lyases
- Cell Membrane
- DNA Primers
- Escherichia coli
- Genes, Bacterial
- Hydrogen-Ion Concentration
- Lysine
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Operon
- Phenotype
- Plasmids
- Polymerase Chain Reaction
- Recombinant Fusion Proteins
- Restriction Mapping