Article
Free amino acid levels in serum and small intestine during the post-natal development of normal and sparse-fur mutant mice.
Comparative biochemistry and physiology. Part A, Physiology - 1 Dec 1994
Malo C
Abstract excerpt
Ornithine transcarbamylase (OTC) is a mitochondrial enzyme which catalyzes the conversion of ornithine into citrulline. In sparse-fur (spf) mutant mice, in which both hepatic and small intestinal OTC are deficient, only small amounts of citrulline are released into the blood. To evaluate the fate of ornithine as well as the levels of substrates and products of these metabolic pathways in normal and OTC-deficient...
Topics
- Amino Acids
- Animals
- Animals, Newborn
- Blood
- Chromatography, High Pressure Liquid
- Hair
- Intestine, Small
- Male
- Mice
- Mice, Inbred ICR
- Mice, Mutant Strains