Article
Characterization of B27 haplotypes by oligotyping and genomic sequencing in the Mexican Mestizo population with ankylosing spondylitis: juvenile and adult onset.
Human immunology - 1 Jul 1995
López-Larrea C, Gonzalez-Roces S, Peña M, Dominguez O, Coto E, Alvarez V, Moreno M, Hernandez O, Burgos-Vargas R, Gorodezky C
Abstract excerpt
The aim of this study was to investigate the contribution of the different B27 subtypes in the Mexican Mestizo population with juvenile and adult AS. No differences in the distribution of B27 subtypes were found between both populations, B*2705 being the predominant subtype followed by B*2702. Transracial gene mapping was performed in order to find out the origin of the B27 alleles of the Mexican Mestizos. A PCR...
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