Article
Undifferentiated spondyloarthropathies in Brazilians: importance of HLA-B27 and the B7-CREG alleles in characterization and disease progression.
The Journal of rheumatology - 1 Dec 2003
Sampaio-Barros Percival D, Conde Roseneide A, Donadi Eduardo A, Kraemer Maria Helena S, Persoli Ligia, Coimbra Ibsen B, Costallat Lilian Teresa L, Samara Adil M, Bértolo Manoel B
Abstract excerpt
OBJECTIVE: To analyze the profile of the HLA-B27 and B7 cross-reactive group (CREG) alleles and the role of these markers in disease characterization and progression in patients with undifferentiated spondyloarthropathies (uSpA). METHODS: A total of 80 patients with a diagnosis of uSpA (40 HLA-B27 positive and 40 HLA-B27 negative) were prospectively studied for 2 years. The control group consisted of 66 HLA-B27...
Topics
- Adolescent
- Alleles
- Brazil
- Child
- Disease Progression
- Female
- Genetic Predisposition to Disease
- HLA-B27 Antigen
- HLA-B7 Antigen
- Humans
- Infant
- Joints
- Male