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Article

Nonresponders to hepatitis B vaccine can present envelope particles to T lymphocytes.

1 Jan 1995

Abstract excerpt

The mechanisms causing nonresponsiveness to hepatitis B surface Ag (HBsAg) vaccines in humans remain largely unknown. The increased incidence of nonresponsiveness in subjects with HLA-DR3 or -DR7 haplotype suggests that immune response mechanisms governed by genes of the MHC are involved. It is conceivable that APC of nonresponders are defective in the presentation of HBsAg because they are unable to adequately...

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Share to Hepatitis B Virus Studies
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PMID: 7814865
DOI: 10.4049/jimmunol.154.2.520

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