Article
Identification in the calcineurin A subunit of the domain that binds the regulatory B subunit.
The Journal of biological chemistry - 6 Jan 1995
Watanabe Y, Perrino B A, Chang B H, Soderling T R
Abstract excerpt
Calcineurin (CaN) is the serine/threonine protein phosphatase (phosphatase 2B) that is activated by binding of Ca2+ to its B subunit and to calmodulin (CaM). This paper identifies residues between the catalytic region and the CaM-binding domain of the A subunit as the domain that binds the regula...
Topics
- Amino Acid Sequence
- Animals
- Baculoviridae
- Base Sequence
- Calcineurin
- Calmodulin-Binding Proteins
- Cells, Cultured
- Cloning, Molecular
- Insecta
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Phosphoprotein Phosphatases
- Protein Binding
- Rats
