Article
Identification and characterization of delta B-CaM kinase and delta C-CaM kinase from rat heart, two new multifunctional Ca2+/calmodulin-dependent protein kinase isoforms.
Biochimica et biophysica acta - 10 Mar 1994
Edman C F, Schulman H
Abstract excerpt
We have identified, expressed and characterized two new isoforms of the multifunctional Ca2+/calmodulin-dependent kinase (CaM kinase) cloned from rat heart. Both isoforms are variants of the neuronal delta-CaM kinase (termed delta A-CaM kinase), and are designated as delta B-CaM kinase and delta...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Calcium-Calmodulin-Dependent Protein Kinases
- Calmodulin
- Cell Line
- Cloning, Molecular
- DNA Primers
- Electrophoresis, Polyacrylamide Gel
- Enzyme Activation
- Genetic Variation
- Isoenzymes
- Kinetics
- Macromolecular Substances
- Molecular Sequence Data
- Molecular Weight
- Mutagenesis, Site-Directed
- Myocardium