Article
Evaluation of flow cytometric methods for diagnosis of chronic granulomatous disease variants under routine laboratory conditions.
Cytometry - 15 Sept 1994
Emmendörffer A, Nakamura M, Rothe G, Spiekermann K, Lohmann-Matthes M L, Roesler J
Abstract excerpt
Neutrophils from 50 pediatric patients with normal phagocyte functions, from 150 healthy adults, from 10 chronic granulomatous disease (CGD)-patients (4 CGD+), and from 18 X-linked carriers for CGD have been tested for their production of H2O2 using staining with dihydrorhodamine 123 and subsequent flow cytometry. Additionally, neutrophils from three patients with myeloperoxidase deficiency were assessed. Cells...
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