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Article

Role of Flow Cytometry in the Diagnosis of Chronic Granulomatous Disease: the Egyptian Experience.

Journal of clinical immunology - 1 Aug 2016

El Hawary Rabab, Meshaal Safa, Deswarte Caroline, Galal Nermeen, Abdelkawy Mahitab, Alkady Radwa, Elaziz Dalia Abd, Freiberger Tomas, Ravcukova Barbora, Litzman Jiri, Bustamante Jacinta, Boutros Jeannette, Gaafar Taghrid, Elmarsafy Aisha

Abstract excerpt

INTRODUCTION: Chronic granulomatous disease (CGD) is an inherited mutational defect in any of the NADPH oxidase complex, CYBB (gp91-phox), NCF1 (p47-phox), CYBA (p22-phox), NCF2 (p67-phox), or NCF4 (p40-phox) leading to inability of phagocytes to perform effective respiratory burst and thus diminished killing of bacteria and fungi. The identification of defective proteins aids in establishing a diagnosis prior to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27222152
DOI: 10.1007/s10875-016-0297-y

Genes

CYBA
CYBB
NCF1
NCF2
NCF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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