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Article

Interpretation of Dihydrorhodamine-1,2,3 Flow Cytometry in Chronic Granulomatous Disease: an Atypical Exemplar.

Journal of clinical immunology - 1 Jul 2022

Donko Agnes, Kuhns Douglas B, Cousin Margot A, Smith Matthew J, Sacco Keith A, Klee Eric W, Joshi Avni Y, Gavrilova Ralitza H, Holland Steven M, Leto Thomas L, Abraham Roshini S

Abstract excerpt

PURPOSE: This is a functional characterization of a novel CYBA variant associated with normal DHR flow cytometry. Chronic granulomatous disease (CGD) is an inborn error of immunity characterized by recurrent bacterial and fungal infections and dysregulated inflammatory responses due to defective phagocytic cell function leading to the formation of granulomas. CGD patients have pathogenic variants in any of the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 35344128
DOI: 10.1007/s10875-022-01217-5

Genes

CYBA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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