Article
Synonymous substitutions are clustered in enterobacterial genes.
Journal of molecular evolution - 1 Nov 1994
Eyre-Walker A
Abstract excerpt
The spatial distribution of synonymous substitutions in enterobacterial genes is investigated. It is shown that synonymous substitutions are significantly clustered in such a way that a synonymous substitution in one codon elevates the rate of synonymous substitution in an adjacent codon by about 10%. The level of clustering does not appear to be related to the level of gene expression, and it is restricted to a...
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