Article
Identification of genetic events involved in early steps of immortalization of mouse fibroblasts.
Biochimica et biophysica acta - 15 Dec 1994
Kaul S C, Wadhwa R, Sugihara T, Obuchi K, Komatsu Y, Mitsui Y
Abstract excerpt
The spontaneously immortalized early passaged fibroblasts from three different strains of mouse are observed to represent two distinct stages of immortalization. The cells at stage I are characterized by slow growth rate, contact inhibition and requisition of serum factors for their growth and pr...
Topics
- Animals
- Calorimetry, Differential Scanning
- Carrier Proteins
- Cell Division
- Cell Line
- Fibroblasts
- HSP70 Heat-Shock Proteins
- Heat-Shock Proteins
- Mice
- Mice, Inbred Strains
- Mice, Nude
- Phenotype