Article
Genetic analysis of the arylamine N-acetyltransferase polymorphism in breast cancer patients.
Oncology - 1 Jan 2000
Agúndez J A, Ladero J M, Olivera M, Abildúa R, Román J M, Benítez J
Abstract excerpt
The association of the arylamine N-acetyltransferase polymorphism and breast cancer has been investigated by analysis of genomic DNA from 160 breast cancer patients and 132 healthy women. Five mutations of the NAT2 gene were studied by using allele-specific PCR amplification and restriction mapping with the endonucleases FokI and Ddel. Eight allelic variants of the NAT2 gene were identified in both, patients with...
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