Characterization and variation of a human inwardly-rectifying-K-channel gene (KCNJ6): a putative ATP-sensitive K-channel subunit.

doi:10.1016/0014-5793(95)00498-x

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Article

Characterization and variation of a human inwardly-rectifying-K-channel gene (KCNJ6): a putative ATP-sensitive K-channel subunit.

FEBS letters - 26 Jun 1995

Sakura H, Bond C, Warren-Perry M, Horsley S, Kearney L, Tucker S, Adelman J, Turner R, Ashcroft F M

Abstract excerpt

The ATP-sensitive K-channel plays a central role in insulin release from pancreatic beta-cells. We report here the cloning of the gene (KCNJ6) encoding a putative subunit of a human ATP-sensitive K-channel expressed in brain and beta-cells, and characterisation of its exon-intron structure. Scree...

Topics

Adenosine Triphosphate
Amino Acid Sequence
Animals
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 21
Cloning, Molecular
Diabetes Mellitus, Type 2
G Protein-Coupled Inwardly-Rectifying Potassium Channels
Genetic Variation
Humans
In Situ Hybridization, Fluorescence
Molecular Sequence Data

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single-Stranded Conformational

Potassium Channels

Potassium Channels, Inwardly Rectifying

Rats

Source

Open in PubMed

Identifiers

PMID: 7796919
DOI: 10.1016/0014-5793(95)00498-x

Genes

KCNJ6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7796919-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.