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Article

Effects of single nucleotide polymorphisms in K(ATP) channel genes on type 2 diabetes in a Turkish population.

Archives of medical research - 1 May 2012

Gonen Mustafa Sait, Arikoglu Hilal, Erkoc Kaya Dudu, Ozdemir Hulya, Ipekci Suleyman Hilmi, Arslan Ahmet, Kayis Seyit Ali, Gogebakan Bulent

Abstract excerpt

BACKGROUND AND AIMS: ATP-sensitive potassium (K(ATP)) channels of pancreatic β-cells play a key role in glucose-stimulated insulin secretion mechanism. The Kir6.2 protein, forming the K(ATP) channel pore inwardly, and the SUR1 protein that surrounds it forming the outside part of the channel were encoded by ABCC8 and KCNJ11 genes, respectively. Recent studies reported that the single nucleotide polymorphisms...

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Share to ATP-Binding Cassette Transporters
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22704848
DOI: 10.1016/j.arcmed.2012.06.001

Genes

ABCC8
KCNJ11

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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