Domain organization of allele-specific replication within the GABRB3 gene cluster requires a biparental 15q11-13 contribution.

doi:10.1038/ng0495-386

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Article

Domain organization of allele-specific replication within the GABRB3 gene cluster requires a biparental 15q11-13 contribution.

Nature genetics - 1 Apr 1995

LaSalle J M, Lalande M

Abstract excerpt

Imprinting marks the parental origin of chromosomes, resulting in allele-specific changes in chromatin organization, transcription and replication. We report a 50-60 kb domain of allele-specific replication between the gamma-aminobutyric acid receptor subunit beta 3 (GABRB3) and alpha 5 (GABRA5)...

Topics

Alleles
Chromosome Mapping
Chromosomes, Human, Pair 15
DNA Replication
Female
Genomic Imprinting
Humans
In Situ Hybridization, Fluorescence
Kinetics
Male
Multigene Family
Receptors, GABA-A
S Phase

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