Article
Domain organization of allele-specific replication within the GABRB3 gene cluster requires a biparental 15q11-13 contribution.
Nature genetics - 1 Apr 1995
LaSalle J M, Lalande M
Abstract excerpt
Imprinting marks the parental origin of chromosomes, resulting in allele-specific changes in chromatin organization, transcription and replication. We report a 50-60 kb domain of allele-specific replication between the gamma-aminobutyric acid receptor subunit beta 3 (GABRB3) and alpha 5 (GABRA5) genes. Replication of this domain occurs in early S phase on the maternal chromosome 15 but is delayed until the end of...
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