Article
Identification of a putative DNA replication origin in the gamma-aminobutyric acid receptor subunit beta3 and alpha5 gene cluster on human chromosome 15q11-q13, a region associated with parental imprinting and allele-specific replication timing.
Gene - 16 Sept 1996
Sinnett D, Woolf E, Xie W, Glatt K, Kirkness E F, Nielsen T O, Zannis-Hadjopoulos M, Price G B, Lalande M
Abstract excerpt
The region containing the GABAA receptor beta3 and alpha5 subunit-encoding genes is subject to parental imprinting and is organized in different allele-specific replication timing domains. A 60-kb domain displaying a maternal early/paternal late pattern of allele-specific replication timing async...
Topics
- Alleles
- Chromosomes, Human, Pair 15
- Cloning, Molecular
- DNA
- DNA Replication
- Genomic Imprinting
- Humans
- Molecular Sequence Data
- Multigene Family
- Nucleic Acid Conformation
- Receptors, GABA-A
- Replication Origin