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Article

Characterization of an ochratoxin-A-dedifferentiated and cloned renal epithelial cell line.

Toxicology and applied pharmacology - 1 Sept 1998

Gekle M, Gassner B, Freudinger R, Mildenberger S, Silbernagl S, Pfaller W, Schramek H

Abstract excerpt

Ochratoxin A (OTA) is a ubiquitous fungal metabolite with predominant nephrotoxic action. OTA impairs postproximal renal electrolyte handling and increases the incidence of renal adenoma and carcinoma. Furthermore, it is supposed to be involved in the pathogenesis of different forms of human renal diseases. Previously we have shown that OTA activates extracellular signal-regulated kinase 1 (ERK1) and ERK2 in the...

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Identifiers

PMID: 9772224
DOI: 10.1006/taap.1998.8509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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