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Article

Phenotypic plasticity in the intercalated cell: the hensin pathway.

The American journal of physiology - 1 Aug 1998

Al-Awqati Q, Vijayakumar S, Hikita C, Chen J, Takito J

Abstract excerpt

The collecting duct of the renal tubule contains two cell types, one of which, the intercalated cell, is responsible for acidification and alkalinization of urine. These cells exist in a multiplicity of morphological forms, with two extreme types, alpha and beta. The former acidifies the urine by an apical proton-translocating ATPase and a basolateral Cl/HCO3 exchanger, which is an alternately spliced form of...

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Identifiers

PMID: 9691006
DOI: 10.1152/ajprenal.1998.275.2.F183

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