Article
Beta 2 adrenergic receptor gene restriction fragment length polymorphism and bronchial asthma.
Thorax - 1 Apr 1995
Ohe M, Munakata M, Hizawa N, Itoh A, Doi I, Yamaguchi E, Homma Y, Kawakami Y
Abstract excerpt
BACKGROUND: Beta 2 adrenergic dysfunction may be one of the underlying mechanisms responsible for atopy and bronchial asthma. The gene encoding the human beta 2 adrenergic receptor (beta 2ADR) has recently been isolated and sequenced. In addition, a two allele polymorphism of this receptor gene has been identified in white people. A study was carried out to determine whether this polymorphism is functionally...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Albuterol
- Alleles
- Asthma
- Bronchi
- Bronchial Provocation Tests
- Child
- Cyclic AMP
- Female
