Article
[The critical significance of a conserved single-stranded interdomain linker in the 5'-untranslated region of poliovirus RNA].
Molekuliarnaia biologiia - 1 Jan 2000
Belov G A, Gmyl' A P, Maslova S V, Pilipenko E V, Agol V I
Abstract excerpt
Translation of polioviral RNA is initiated by interaction of a small ribosomal subunit with internal segments of the 5'-untranslated region (5'UTR). Several mutations were constructed within 5'UTR segment 425-449. All of them (including a single C444-->U replacement) inhibited in vitro translatio...
Topics
- Base Sequence
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Poliovirus
- Protein Biosynthesis
- RNA, Viral
