Article
Dopamine transporter gene polymorphism and alcoholism.
Biochemical and biophysical research communications - 6 Jun 1995
Muramatsu T, Higuchi S
Abstract excerpt
In this search for a possible association between the dopamine transporter gene (DAT1) polymorphism and alcoholism, 655 Japanese alcoholics were grouped according to their aldehyde dehydrogenase-2 (ALDH2) genotypes. Because inactive ALDH2 is an established negative risk factor for alcoholism, alcoholics with the mutant allele, ALDH2*2, were considered a relatively homogeneous group. The frequency of the 7-repeat...
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