Article
Escherichia coli RecG and RecA proteins in R-loop formation.
The EMBO journal - 15 May 1995
Hong X, Cadwell G W, Kogoma T
Abstract excerpt
Escherichia coli rnhA mutants devoid of RNase HI exhibit constitutive stable DNA replication, cSDR, which is thought to be initiated from R-loops stabilized in the absence of RNase HI. We found that a combination of an rnhA and a recG mutation is lethal to the cell. recG mutations that inactivate the helicase activity of RecG protein and inhibit reverse branch migration of Holliday junctions impart phenotypes...
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