Article
RecA, Tus protein and constitutive stable DNA replication in Escherichia coli rnhA mutants.
Molecular & general genetics : MGG - 1 Sept 1994
Kogoma T, Barnard K G, Hong X
Abstract excerpt
Constitutive stable DNA replication (cSDR), which uniquely occurs in Escherichia coli rnhA mutants deficient in ribonuclease HI activity, requires RecA function. The recA428 mutation, which inactivates the recombinase activity but imparts a constitutive coprotease activity, blocks cSDR in rnhA mutants. The result indicates that the recombinase activity of RecA, which promotes homologous pairing and strand...
Topics
- Bacterial Proteins
- Chromosomes, Bacterial
- DNA Nucleotidyltransferases
- DNA Replication
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Proteins
- Genes, Bacterial
- Mutation
- Nucleic Acid Conformation
- Rec A Recombinases
