Embryonic tissue differentiation in Caenorhabditis elegans requires dif-1, a gene homologous to mitochondrial solute carriers.

doi:10.1002/j.1460-2075.1995.tb07225.x

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Article

Embryonic tissue differentiation in Caenorhabditis elegans requires dif-1, a gene homologous to mitochondrial solute carriers.

The EMBO journal - 15 May 1995

Ahringer J

Abstract excerpt

The dif-1 gene was identified in a general screen for maternal-effect embryonic lethal (Mel) mutants. dif-1 mutant embryos complete gastrulation and embryonic cell division normally, but then arrest development with only a small amount of tissue differentiation. Either maternal or zygotic dif-1 activity is sufficient for wild-type development. The temperature-sensitive period of a cold-sensitive dif-1 mutant...

Topics

Amino Acid Sequence
Animals
Base Sequence
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Carrier Proteins
Digestive System
Genes, Helminth
Helminth Proteins
Membrane Transport Proteins
Mitochondria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Morphogenesis

Mutation

Phenotype

RNA, Messenger

Sequence Homology, Amino Acid

Skin

Source

Open in PubMed Open full text

Identifiers

PMID: 7774589
DOI: 10.1002/j.1460-2075.1995.tb07225.x
PMCID: PMC398338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7774589-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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