Article
Imprinted genes: identification by chromosome rearrangements and post-genomic strategies.
Trends in genetics : TIG - 1 Jul 2002
Oakey Rebecca J, Beechey Colin V
Abstract excerpt
Imprinted genes are differentially expressed from the maternally and paternally inherited alleles. Accordingly, inheritance of both copies of an imprinted chromosome or region from a single parent leads to the mis-expression of the imprinted genes present in the selected region. Strains of mice with reciprocal and Robertsonian chromosomal translocations or mice with engineered chromosomal rearrangements can be...
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