Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of T helper type 2 cell differentiation by murine Schnurri-2.

The Journal of experimental medicine - 7 Feb 2005

Kimura Motoko Y, Hosokawa Hiroyuki, Yamashita Masakatsu, Hasegawa Akihiro, Iwamura Chiaki, Watarai Hiroshi, Taniguchi Masaru, Takagi Tsuyoshi, Ishii Shunsuke, Nakayama Toshinori

Abstract excerpt

Schnurri (Shn) is a large zinc finger protein implicated in cell growth, signal transduction, and lymphocyte development. Vertebrates possess at least three Shn orthologues (Shn-1, Shn-2, and Shn-3), which appear to act within the bone morphogenetic protein, transforming growth factor beta, and activin signaling pathways. However, the physiological functions of the Shn proteins remain largely unknown. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Bone Marrow Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CD4-Positive T-Lymphocytes

Share to GATA3 Transcription Factor

Share to NF-kappa B

Share to Protein Isoforms

Share to Receptors, Antigen, T-Cell

Share to Th2 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 15699073
DOI: 10.1084/jem.20040733
PMCID: PMC2213028

Genes

GATA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of T helper type 2 cell differentiation by murine Schnurri-2.PMID 15699073Read ↗

The Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family.Semantic proximity Read ↗

Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3.Semantic proximity Read ↗

Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1.Semantic proximity Read ↗

NFAT pulls the strings during CD4+ T helper cell effector functionsSemantic proximity Read ↗

A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling.Semantic proximity Read ↗

Sox12 enhances Fbw7-mediated ubiquitination and degradation of GATA3 in Th2 cellsSemantic proximity Read ↗

Transcriptional activation of TINF2, a gene encoding the telomere-associated protein TIN2, by Sp1 and NF-κB factors.Semantic proximity Read ↗

Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.Semantic proximity Read ↗

Control of bone resorption in mice by Schnurri-3.Semantic proximity Read ↗

Sprouty Proteins Are Negative Regulators of Interferon (IFN) Signaling and IFN-inducible Biological ResponsesSemantic proximity Read ↗

Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros.Semantic proximity Read ↗

The Caenorhabditis elegans gene sem-4 controls neuronal and mesodermal cell development and encodes a zinc finger protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.