Article
Basic mechanisms in rheumatoid arthritis: the role of T lymphocytes in rheumatoid synovitis.
Advances in prostaglandin, thromboxane, and leukotriene research - 1 Jan 1994
Alsalameh S, Burmester G R, Kalden J R
Abstract excerpt
Undoubtedly, synovitis is a cell-mediated process involving various cell types, such as T cells, B cells, APC, monocytes/macrophages, synoviocytes, chondrocytes, and cytokines. Therefore, it is difficult to clarify the cell type that plays the central role in the inflammatory process. Despite this difficulty, there is strong evidence that T cells mediate the disease in collaboration with APC that bear specific...
Topics
- Animals
- Arthritis, Rheumatoid
- Cytokines
- Phenotype
- Receptors, Antigen, T-Cell
- Synovitis
- T-Lymphocytes