Article
QTL-based evidence for the role of epistasis in evolution.
Genetical research - 1 Oct 2005
Malmberg Russell L, Mauricio Rodney
Abstract excerpt
The extent to which epistasis contributes to adaptation and speciation has been a controversial topic in evolutionary genetics. One experimental approach to study epistasis is based on quantitative trait locus (QTL) mapping using molecular markers. Comparisons can be made among all possible pair-wise combinations of the markers, irrespective of whether an additive QTL is associated with a marker; several software...
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