A nonparametric approach for mapping quantitative trait loci.

doi:10.1093/genetics/139.3.1421

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Article

A nonparametric approach for mapping quantitative trait loci.

Genetics - 1 Mar 1995

Kruglyak L, Lander E S

Abstract excerpt

Genetic mapping of quantitative trait loci (QTLs) is performed typically by using a parametric approach, based on the assumption that the phenotype follows a normal distribution. Many traits of interest, however, are not normally distributed. In this paper, we present a nonparametric approach to...

Topics

Animals
Chromosome Mapping
Chromosomes
Crosses, Genetic
Genetic Markers
Genome
Genotype
Humans
Mice
Normal Distribution
Phenotype
Statistics, Nonparametric

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