Article
[1,4-dihydroisonicotinic acid (1,4-DHINA) derivatives, inhibitors of chemical mutagenesis].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 1995
Goncharova R I, Kuzhir T D, Dalivelia O V, Dubur G Ia, Uldrikis Ia R
Abstract excerpt
The paper summarizes the results of studies into the modifying effect of some 1,4-dihydroisonicotinic acid (1,4-DHINA) derivatives during chemical mutagenesis in eukaryotic organisms. The compounds under study are effective in reducing the incidence of point and chromosomal mutations induced by e...
Topics
- Animals
- Antimutagenic Agents
- Bone Marrow
- Cells, Cultured
- Chromosome Aberrations
- Drosophila melanogaster
- Ethyl Methanesulfonate
- Female
- Genotype
- Humans
- Isonicotinic Acids
- Lymphocytes
- Male
- Mice
- Middle Aged
- Mutagenesis
- Oocytes
- Spermatozoa
