Article
[Mechanisms of the inhibitive action of 1,4-dihydroisonicotinic acid derivatives in chemical mutagenesis].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 1995
Kuzhir T D, Goncharova R I
Abstract excerpt
1.4-Dihydroisonicotinic acid derivatives were used as an example to examine the mechanisms of action of exogenous antimutagens in chemical mutagenesis in eukaryotic organisms. The chemical mutagenesis was stimulated by alkylating agents, mutagens of direct action. The behaviour of alkylating muta...
Topics
- Alkylating Agents
- Animals
- Antimutagenic Agents
- Antioxidants
- Bone Marrow
- Bone Marrow Cells
- Cells, Cultured
- Chromosome Aberrations
- DNA
- DNA Repair
- Drosophila melanogaster
- Ethyl Methanesulfonate
- Female
- Humans
- Isonicotinic Acids
- Lymphocytes
- Male
- Mice
