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Article

Cloning of the ATP phosphoribosyl transferase gene of Corynebacterium glutamicum and application of the gene to L-histidine production.

Bioscience, biotechnology, and biochemistry - 1 Apr 1994

Mizukami T, Hamu A, Ikeda M, Oka T, Katsumata R

Abstract excerpt

Corynebacterium glutamicum mutants lacking ATP phosphoribosyl transferase (PRT) were selected by complementation with the Escherichia coli PRT gene. The recombinant plasmid pCH13 carrying a wild type PRT gene from C. glutamicum T106 was obtained in one of the mutants, LH13. Transformants, LH13/pCH13 and T106/pCH13, had three times higher PRT specific activity than T106. The plasmid pCH99 specifying the PRT, which...

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Identifiers

PMID: 7764856
DOI: 10.1271/bbb.58.635

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