Effects of dietary fat on high-density-lipoprotein subclasses are influenced by both apolipoprotein E isoforms and low-density-lipoprotein subclass patterns.

Abstract excerpt

We examined the effects of replacing dietary fat with carbohydrates on high-density-lipoprotein (HDL) subclasses as measured by nondenaturing polyacrylamide-gradient-gel electrophoresis. One hundred five men received a 6-wk low-fat diet (24% of total energy) and a 6-wk high-fat diet (46% of energy) in a crossover design. Absorbency of protein stain was measured within five HDL subclasses: HDL3c (7.2-7.8 nm),...

Topics

• Apolipoproteins E
• Body Mass Index
• Cholesterol
• Dietary Carbohydrates
• Dietary Fats
• Electrophoresis
• Humans
• Lipoproteins, HDL
• Lipoproteins, LDL
• Male
• Particle Size