Article
Apolipoprotein A1 genotype affects the change in high density lipoprotein cholesterol subfractions with exercise training.
Atherosclerosis - 1 Mar 2006
Ruaño Gualberto, Seip Richard L, Windemuth Andreas, Zöllner Stefan, Tsongalis Gregory J, Ordovas Jose, Otvos James, Bilbie Cherie, Miles Mary, Zoeller Robert, Visich Paul, Gordon Paul, Angelopoulos Theodore J, Pescatello Linda, Moyna Niall, Thompson Paul D
Abstract excerpt
High density lipoprotein cholesterol (HDL-C) is a primary risk factor for cardiovascular disease. Apolipoprotein A-1 (apoA1) is the major HDL-associated apolipoprotein. The -75G/A single nucleotide polymorphism (SNP) in the apolipoprotein A1 gene (APOA1) promoter has been reported to be associated with HDL-C concentrations as well as HDL-C response to dietary changes in polyunsaturated fat intake. We examined the...
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