Article
Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation.
Genes & development - 15 May 1995
Takeuchi T, Yamazaki Y, Katoh-Fukui Y, Tsuchiya R, Kondo S, Motoyama J, Higashinakagawa T
Abstract excerpt
A mouse mutation, termed jumonji (jmj), was generated by a gene trap strategy. Expression of the trapped gene (jmj gene), as monitored by X-gal staining, was detected predominantly at the midbrain-hindbrain boundary and in the cerebellum, depending on the stage of development. All embryos homozyg...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Brain
- DNA Primers
- Gene Expression Regulation, Developmental
- Genes
- Genetic Vectors
- Mice
- Mice, Mutant Strains
- Molecular Sequence Data
- Nerve Tissue Proteins
- Nervous System
- Phenotype
- Polycomb Repressive Complex 2
- RNA, Messenger