Article
Jumbled spine and ribs (Jsr): a new mutation on mouse chromosome 5.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 1999
Miyoshi H, Kon Y, Seo K W, Jin H K, Hasegawa A, Watanabe T
Abstract excerpt
Jumbled spine and ribs (Jsr) is an autosomal dominant mutation that results in malformation of the axial skeleton. The vertebrae of mutant mice (Jsr/+) are all shorter than those of normal mice (+/+) in the inbred line and show various abnormalities. In addition, several ribs are fused at their proximal region because of fusion of thoracic vertebrae. In this study, we localized the Jsr mutation on distal...
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