Article
Capping protein levels influence actin assembly and cell motility in dictyostelium.
Cell - 19 May 1995
Hug C, Jay P Y, Reddy I, McNally J G, Bridgman P C, Elson E L, Cooper J A
Abstract excerpt
Actin assembly is important for cell motility, but the mechanism of assembly and how it relates to motility in vivo is largely unknown. In vitro, actin assembly can be controlled by proteins, such as capping protein, that bind filament ends. To investigate the function of actin assembly in vivo, we altered the levels of capping protein in Dictyostelium cells and found changes in resting and...
Topics
- Actin Depolymerizing Factors
- Actins
- Animals
- Cell Movement
- Destrin
- Dictyostelium
- Microfilament Proteins
- Mutation