Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificity.

Cell - 19 May 1995

Symons J A, Alcamí A, Smith G L

Abstract excerpt

Vaccinia virus (VV) and other orthopoxviruses express a soluble type I interferon (IFN) receptor that for VV strain Western Reserve is encoded by gene B18R. The 60-65 kDa glycoprotein is related to the interleukin-1 receptors and is a member of the immunoglobulin superfamily, unlike other type I IFN receptors, which belong to the class II cytokine receptor family. The receptor has high affinity (KD, 174 pM) for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Interferon-alpha
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Mutation

Share to Rabbits

Share to Species Specificity

Source

Identifiers

PMID: 7758109
DOI: 10.1016/0092-8674(95)90076-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificity.PMID 7758109Read ↗

Vaccinia Virus B18R Gene Encodes a Type I Interferon-binding Protein That Blocks Interferon α Transmembrane SignalingSemantic proximity Read ↗

A study of the vaccinia virus interferon-γ receptor and its contribution to virus virulenceSemantic proximity Read ↗

Vaccinia, cowpox, and camelpox viruses encode soluble gamma interferon receptors with novel broad species specificitySemantic proximity Read ↗

Vaccinia virus strain Western Reserve protein B14 is an intracellular virulence factor.Semantic proximity Read ↗

RNA-Seq Based Transcriptome Analysis of the Type I Interferon Host Response upon Vaccinia Virus Infection of Mouse Cells.Semantic proximity Read ↗

Ectromelia, vaccinia and cowpox viruses encode secreted interleukin-18-binding proteinsSemantic proximity Read ↗

Vaccinia virus strains Lister, USSR and Evans express soluble and cell-surface tumour necrosis factor receptors.Semantic proximity Read ↗

Inhibition of type I and type III interferons by a secreted glycoprotein from Yaba-like disease virusSemantic proximity Read ↗

Human interferon-ϵ and interferon-κ exhibit low potency and low affinity for cell-surface IFNAR and the poxvirus antagonist B18R.Semantic proximity Read ↗

Viral soluble decoy receptor as a novel treatment for IFN-I triggered diseasesSemantic proximity Read ↗

A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: unveiling a novel virulence factorSemantic proximity Read ↗

Vaccinia Virus Tropism for Primary Hematolymphoid Cells Is Determined by Restricted Expression of a Unique Virus ReceptorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.